Brain diseases, particularly glioblastoma multiforme (GBM), are challenging to treat due to the blood-brain barrier and recurrence rates. While tumour resection offers temporary relief, cancer stem cells typically remain, causing recurrence in most patients within four years. This research aims to create degradable implantable electronics that can both detect GBM markers and release therapeutic drugs. The device will signal recurrence, then gradually degrade to release treatment. This interdisciplinary project combines drug delivery, materials science, and tissue engineering to advance the field of implantable electronics in brain therapy.